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Western blot analysis in MCF-7 cell line and human placenta tissue lysates (35ug/lane).
Western blot analysis in MCF-7 cell line and human placenta tissue lysates (35ug/lane).

ESR2 Antibody

CATALOG NUMBER: 60-578

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This ESR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-480 amino acids from the C-terminal region of human ESR2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
59 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ESR2
Additional Names:
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2, ESR2, ESTRB, NR3A2
Protein Accession Number:
Q92731
Protein Gi Number:
6166154
Ncbi Gene Id Number:
2100
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
Background Reference 1:
Fang, Y.J., et al. Tumour Biol. 31(6):651-658(2010) Hayes, D.F., et al. Clin. Pharmacol. Ther. 88(5):626-629(2010) Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010)Wurster, M., et al. Oncol. Rep. 24(3):653-659(2010) Paulus, J.K., et al. Lung Cancer (2010) In press :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-578

List Size:
400 ul

List Price:

$495.00

Datasheet
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