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Western blot analysis in A2058 cell line lysates (35ug/lane).
Western blot analysis in A2058 cell line lysates (35ug/lane).

BLOC1S3 Antibody

CATALOG NUMBER: 60-771

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This BLOC1S3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-202 amino acids from the C-terminal region of human BLOC1S3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
21 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
BLOC1S3
Additional Names:
Biogenesis of lysosome-related organelles complex 1 subunit 3, BLOC-1 subunit 3, BLOC1S3, BLOS3
Protein Accession Number:
Q6QNY0
Protein Gi Number:
74749299
Ncbi Gene Id Number:
388552
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein that is a component of theBLOC1 multi-subunit protein complex. This complex is necessary forthe biogenesis of specialized organelles of the endosomal-lysosomalsystem, including platelet dense granules and melanosomes.Mutations in this gene cause Hermansky-Pudlak syndrome 8, a diseasecharacterized by lysosomal storage defects, bleeding due toplatelet storage pool deficiency, and oculocutaneous albinism.
Background Reference 1:
Seshadri, S., et al. JAMA 303(18):1832-1840(2010)
Background Reference 2:
Lowe, J.K., et al. PLoS Genet.(2), E1000365 (2009) :
Background Reference 3:
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Background Reference 4:
Morgan, N.V., et al. Am. J. Hum. Genet. 78(1):160-166(2006)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-771

List Size:
400 ul

List Price:

$495.00

Datasheet
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