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Western Blot at 1:2000 dilution Lane 1: T47D whole cell lysates Lane 2: human kidney lysates Lane 3: KG-1 whole cell lysates Lane 4: human liver lysates Lysates/proteins at 20 ug per lane.
Western Blot at 1:2000 dilution Lane 1: T47D whole cell lysates Lane 2: KG-1 whole cell lysates Lane 3: human liver lysates Lysates/proteins at 20 ug per lane.
Western blot analysis in T47D cell line lysates (35ug/lane).
Western Blot at 1:2000 dilution Lane 1: T47D whole cell lysates Lane 2: human kidney lysates Lane 3: KG-1 whole cell lysates Lane 4: human liver lysates Lysates/proteins at 20 ug per lane.

HAVCR2 Antibody

CATALOG NUMBER: 60-816

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This HAVCR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-194 amino acids from the Central region of human HAVCR2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:2000
Predicted Molecular Weight:
33 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HAVCR2
Additional Names:
Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3, HAVCR2, TIM3, TIMD3
Protein Accession Number:
Q8TDQ0
Protein Gi Number:
311033536
Ncbi Gene Id Number:
84868
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CD4 (MIM 186940)-positive T helper lymphocytes can bedivided into types 1 (Th1) and 2 (Th2) on the basis of theircytokine secretion patterns. Th1 cells and their associatedcytokines are involved in cell-mediated immunity to intracellularpathogens and delayed-type hypersensitivity reactions, whereas Th2cells are involved in the control of extracellular helminthicinfections and the promotion of atopic and allergic diseases. The 2types of cells also cross-regulate the functions of the other. TIM3is a Th1-specific cell surface protein that regulates macrophageactivation and enhances the severity of experimental autoimmuneencephalomyelitis in mice.
Background Reference 1:
Cao, B., et al. Cancer Immunol. Immunother. 59(12):1851-1857(2010)
Background Reference 2:
Dorfman, D.M., et al. Hum. Pathol. 41(10):1486-1494(2010)
Background Reference 3:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 4:
Dardalhon, V., et al. J. Immunol. 185(3):1383-1392(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-816

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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