ITGB1BP3 Antibody

CATALOG NUMBER: 61-506

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ITGB1BP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITGB1BP3.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
26 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
NMRK2
Additional Names:
Nicotinamide riboside kinase 2, NRK 2, NmR-K 2, Integrin beta-1-binding protein 3, Muscle integrin-binding protein, MIBP, Nicotinic acid riboside kinase 2, Ribosylnicotinamide kinase 2, RNK 2, Ribosylnicotinic acid kinase 2, NMRK2, ITGB1BP3, NRK2
Protein Accession Number:
Q9NPI5
Protein Gi Number:
50401178
Ncbi Gene Id Number:
27231
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ITGB1BP3 catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The protein reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. It is involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation and may play a role in the regulation of terminal myogenesis.
Background Reference 1:
Bieganowski,P., Cell 117 (4), 495-502 (2004)
Background Reference 2:
Li,J., J. Cell Biol. 147 (7), 1391-1398 (1999)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-506

List Size:
400 ul

List Price:

$495.00

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