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Western blot analysis of CHRNA3 Antibody in CEM cell line lysates (35ug/lane)
CHRNA3 Antibody IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis of CHRNA3 Antibody in CEM cell line lysates (35ug/lane)

CHRNA3 Antibody

CATALOG NUMBER: 61-758

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This CHRNA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human CHRNA3.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
57 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CHRNA3
Additional Names:
Neuronal acetylcholine receptor subunit alpha-3, CHRNA3, NACHRA3
Protein Accession Number:
P32297
Protein Gi Number:
254763435
Ncbi Gene Id Number:
1136
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CHRNA3 locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
Background Reference 1:
Cho, M.H., et al. Nat. Genet. 42(3):200-202(2010)
Background Reference 2:
Girard, N., et al. Clin. Cancer Res. 16(2):755-763(2010)
Background Reference 3:
Grando, S.A., et al. J. Invest. Dermatol. 105(6):774-781(1995)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-758

List Size:
400 ul

List Price:

$495.00

Datasheet
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