TMIE Antibody

CATALOG NUMBER: 64-099

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This TMIE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the Central region of human TMIE.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
17 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TMIE
Additional Names:
Transmembrane inner ear expressed protein, TMIE
Protein Accession Number:
Q8NEW7
Protein Gi Number:
212276469
Ncbi Gene Id Number:
259236
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. This gene is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment.
Background Reference 1:
Yang, J.J., et al. Int. J. Pediatr. Otorhinolaryngol. (2010) In press
Background Reference 2:
Sirmaci, A., et al. Clin. Genet. 75(6):562-567(2009)
Background Reference 3:
Santos, R.L., et al. J. Mol. Med. 84(3):226-231(2006)
Background Reference 4:
Cho, K.I., et al. Comp. Med. 53(6):642-648(2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

64-099

List Size:
400 ul

List Price:

$495.00

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