SNX27 Antibody

CATALOG NUMBER: 64-201

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This SNX27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-340 amino acids from the Central region of human SNX27.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
61 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SNX27
Additional Names:
Sorting nexin-27, SNX27, KIAA0488
Protein Accession Number:
Q96L92
Protein Gi Number:
166214988
Ncbi Gene Id Number:
81609
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SNX27 encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein.
Background Reference 1:
Lunn, M.L., et al. Nat. Neurosci. 10(10):1249-1259(2007)
Background Reference 2:
Nassirpour, R., et al. Channels (Austin) 1(5):331-333(2007)
Background Reference 3:
MacNeil, A.J., et al. Biochem. Biophys. Res. Commun. 359(4):848-853(2007)
Background Reference 4:
Rincon, E., et al. Mol. Cell Proteomics 6(6):1073-1087(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

64-201

List Size:
400 ul

List Price:

$495.00

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