Recombinant

SARS-CoV-2 Spike RBD Antibody, monoclonal, Chimeric

CATALOG NUMBER: 11-582

Clonality:
Recombinant Monoclonal
Tested Applications:
ELISA, WB
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Species Reactivity:
Mouse
Immunogen:
Anti-SARS-CoV-2 Spike RBD Antibody, Human IgM is a chimeric monoclonal antibody combining the constant domains of the human IgM molecule with mouse variable regions.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Specificity:
This product can recognize SARS-CoV-2 and SARS-CoV Spike Protein RBD domainn. No cross-reactivity is detected with Spike Protein RBD domain of other coronaviruses, including MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.
Purification:
>85% as determined by SDS-PAGE.
Clonality:
Recombinant Monoclonal
Isotype:
Human IgM, Kappa
Physical State:
Lyophilized
Buffer:
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 . Normally trehalose is added as protectant before lyophilization.
Concentration:
batch dependent
Storage Conditions:
For long term storage, the product should be stored at lyophilized state at -20°C or lower..Please avoid repeated freeze-thaw cycles.This product is stable after storage at:.-20 to -70°C for 12 months in lyophilized state from date of receipt;.-70°C for 3 months under sterile conditions after reconstitution.
Ncbi Official Symbol:
S
Additional Names:
spike glycoprotein
Ncbi Gene Id Number:
43740568
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

11-582

List Size:
0.1 mg

List Price:

$535.00

Out of stock

Shipping Info
Customize your order
Custom Antibody Services

New & Featured Products

CATALOG NUMBER: PM-7369-HRP

CATALOG NUMBER: PM-7369-biotin

CATALOG NUMBER: PM-7369