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RIG-I Antibody [Alme-1] (biotin)

CATALOG NUMBER: 36-103

Clonality:
Monoclonal
Tested Applications:
IHC, IP, WB
Host Species:
Mouse
Species Reactivity:
Human, Mouse
Conjugate:
Biotin
Specifications
Host Species:
Mouse
Species Reactivity:
Human, Mouse
Immunogen:
Recombinant human RIG-I (aa 201-713).
Conjugate:
Biotin
Tested Applications:
IHC, IP, WB
Application Note:
Immunohistochemistry: (paraffin sections). Immunoprecipitation: (1:200). Western blot: (1:1,000).
Specificity:
Recognizes human and mouse RIG-I.
Purification:
>95% (SDS-PAGE)
Clonality:
Monoclonal
Isotype:
IgG1
physical-state:
Liquid
Buffer:
Liquid. In PBS containing 0.02% sodium azide.
Concentration:
0.5 mg/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C.
Ncbi Official Symbol:
DDX58
Additional Names:
RIG-1; Retinoic Acid-inducible Gene 1 Protein; DEAD-box Protein 58; Probable ATP-dependent RNA Helicase DDX58
Protein Accession Number:
81170421
Protein Gi Number:
O95786
Ncbi Gene Id Number:
23586
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5’-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-I recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-103

List Size:
100 ug

List Price:

$627.00

Datasheet
Shipping Info

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