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BTLA Antibody [6F4]

CATALOG NUMBER: 36-160

Clonality:
Monoclonal
Tested Applications:
ELISA, Flow, Functional Assays
Host Species:
Rat
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rat
Species Reactivity:
Human
Immunogen:
Ectodomain of human BTLA fused to human IgG Fc.
Conjugate:
Unconjugated
Tested Applications:
ELISA, Flow, Functional Assays
Application Note:
Immunohistochemistry: (frozen sections).
Specificity:
Recognizes human BTLA.
Purification:
>95% (SDS-PAGE)
Clonality:
Monoclonal
Isotype:
IgG1
physical-state:
Liquid
Buffer:
Liquid. In PBS containing 10% glycerol.
Concentration:
1 mg/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C.
Ncbi Official Symbol:
BTLA
Additional Names:
B and T Lymphocyte Associated; Lymphotoxin-beta Receptor; Tumor Necrosis Factor Receptor 2 Related Protein; Tumor Necrosis Factor C Receptor; Tumor Necrosis Factor Receptor Superfamily Member 3; TNFRSF3
Protein Accession Number:
145580621
Protein Gi Number:
NP_861445
Ncbi Gene Id Number:
151888
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
B and T lymphocyte associated (BTLA) is an Ig domain superfamily protein with cytoplasmic immunoreceptor tyrosine-based inhibitory motifs. The herpes virus entry mediator (HVEM), a member of the TNF receptor (TNFR) superfamily, can act as a molecular switch that modulates T cell activation by propagating positive signals from the TNF-related ligand LIGHT (TNFR superfamily 14), or inhibitory signals through the Ig superfamily member BTLA. The binding site on HVEM for BTLA is conserved in the orphan TNF receptor UL144, present in human CMV. UL144 binds BTLA, but not LIGHT, and inhibits T cell proliferation, selectively mimicking the inhibitory cosignaling function of HVEM.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-160

List Size:
100 ug

List Price:

$540.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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