IL-37 Antibody

CATALOG NUMBER: 36-313

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, IP, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Recombinant human IL-37.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, IP, WB
Application Note:
ELISA: (direct and indirect: 1:2,000-1:5,000), Immunohistochemistry: (1:50)Immunoprecipitation: (1:500- 1:2,000). Western Blot: (1:2,000-1:5,000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
Specificity:
Recognizes human IL-37. Detects a band of ~30kDa by Western blot.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Storage Conditions:
Stable for at least 6 months after receipt when stored at -20°C.
Ncbi Official Symbol:
IL37
Additional Names:
Interleukin-1 Family Member 7; IL-1F7; FIL1 zeta; IL-1X; Interleukin-1 Homolog 4; IL-1H4; Interleukin-1 zeta; IL-1 zeta; IL-1RP1; IL1F7; FIL1Z, IL1H4, IL1RP1
Protein Accession Number:
20127524
Protein Gi Number:
NP_055254
Ncbi Gene Id Number:
27178
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
IL-37 (Interleukin-37) belongs to the IL-1 family. It binds to interleukin-18 receptor (IL-18R) but not to IL-1 receptor. It was shown to play an important role as a link between innate and adaptive immunity and it is suggested as a new player in the inflammatory and immune responses mediated by the IL-18/IL-18R axis. It was also shown to inhibit tumor growth.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-313

List Size:
100 ug

List Price:

$408.00

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