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Antibody used in WB on Human Raji at 0.2-1 ug/ml.
Antibody used in WB on Human Raji at 0.2-1 ug/ml.

FGD1 Antibody

CATALOG NUMBER: 27-391

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FGD1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
FGD1 antibody can be used for detection of FGD1 by ELISA at 1:312500. FGD1 antibody can be used for detection of FGD1 by western blot at 2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1207 - Raji Cell Lysate
Predicted Molecular Weight:
107 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store FGD1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
FGD1
Additional Names:
FGD1, AAS, FGDY, MRXS16, ZFYVE3
Protein Accession Number:
NP_004454
Protein Gi Number:
24797153
Ncbi Gene Id Number:
2245
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.
Background Reference 1:
Lebel, R.R., et al., (2002) Clin. Genet. 61 (2), 139-145.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-391

List Size:
100 ul

List Price:

$519.00

Datasheet
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