TBX19 Antibody

CATALOG NUMBER: 27-564

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat, Zebrafish
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat, Zebrafish
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBX19.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
TBX19 antibody can be used for detection of TBX19 by ELISA at 1:62500. TBX19 antibody can be used for detection of TBX19 by western blot at 1.0-1.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
48 kDa
Purification:
Antibody is supplied as total IgG.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store TBX19 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
TBX19
Additional Names:
TBX19, TPIT, TBS19, dJ747L4.1
Protein Accession Number:
NP_005140
Protein Gi Number:
4827024
Ncbi Gene Id Number:
9095
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX19 is the human ortholog of mouse Tbx19/Tpit gene. Studies in mouse show that Tpit protein is present only in the two pituitary pro-opiomelanocortin (POMC)-expressing lineages, the corticotrophs and melanotrophs. Mutations in the human ortholog were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage.
Background Reference 1:
Maira, M., et al., (2003) J.Biol.Chem.278(47), 46523-46532.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-564

List Size:
100 ul

List Price:

$473.00

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