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Antibody used in WB on Human Heart at 0.2-1 ug/ml.
Antibody used in WB on Human HepG2 at 1 ug/ml.
Antibody used in WB on Human Hela at 1 ug/ml.
Antibody used in WB on Human Heart at 0.2-1 ug/ml.

XPO1 Antibody

CATALOG NUMBER: 29-311

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human XPO1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
XPO1 antibody can be used for detection of XPO1 by ELISA at 1:62500. XPO1 antibody can be used for detection of XPO1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Predicted Molecular Weight:
123 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store XPO1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
XPO1
Additional Names:
XPO1, CRM1, DKFZp686B1823, emb, exp1
Protein Accession Number:
NP_003391
Protein Gi Number:
4507943
Ncbi Gene Id Number:
7514
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. XPO1 also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background Reference 1:
Cheong, J.K., (2008) J. Biol. Chem. 283 (17), 11661-11676.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

29-311

List Size:
100 ul

List Price:

$519.00

Datasheet
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