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Antibody used in WB on Human Jurkat 0.2-1 ug/ml.
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.

ZMPSTE24 Antibody

CATALOG NUMBER: 30-216

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZMPSTE24.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
ZMPSTE24 antibody can be used for detection of ZMPSTE24 by ELISA at 1:312500. ZMPSTE24 antibody can be used for detection of ZMPSTE24 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
55 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store ZMPSTE24 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
ZMPSTE24
Additional Names:
ZMPSTE24, FACE-1, FACE1, FLJ14968, STE24, Ste24p, HGPS, PRO1
Protein Accession Number:
NP_005848
Protein Gi Number:
18379366
Ncbi Gene Id Number:
10269
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
Background Reference 1:
Moulson, C.L., (2005) J. Invest. Dermatol. 125 (5), 913-919.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

30-216

List Size:
100 ul

List Price:

$519.00

Datasheet
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