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CD61 Antibody [VI-PL2]

CATALOG NUMBER: 76-175

Clonality:
Monoclonal
Tested Applications:
Flow, Functional Assays, IHC, WB
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Tested Applications:
Flow, Functional Assays, IHC, WB
Specificity:
The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography.
Clonality:
Monoclonal
Isotype:
mouse IgG1, kappa
physical-state:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C . Do not freeze.
Ncbi Official Symbol:
ITGB3
Additional Names:
GT, CD61, GP3A, BDPLT2, GPIIIa, BDPLT16, ITGB3
Ncbi Gene Id Number:
3690
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3. CD61 forms a complex with CD41 (platelet gpIIb) and CD51 (integrin alphaV). It is expressed on osteoclasts, fibroblasts, platelets, macrophages, and megakaryocytes and appears to bind to fibronectin, vitronectin, thrombospondin, and fibrinogen and vWF. The VI-PL2 antibody is reported to be cross-reactive with baboon, rhesus, and cynomolgus.
Background Reference 1:
Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.
Background Reference 2:
Barrett, L., Dai, C., Gamberg, J., Gallant, M., Grant, M. (2007). Circulating CD14 CD36+ peripheral blood mononuclear cells constitutively produce interleukin-10.Journal of leukocyte biology,82(1), 152-160.
Background Reference 3:
Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-175

List Size:
0.1 mg

List Price:

$302.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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