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CD83 Antibody [Michel17] (PE)

CATALOG NUMBER: 76-317

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
PE
Specifications
Host Species:
Rat
Species Reactivity:
Mouse
Conjugate:
PE
Tested Applications:
Flow
Specificity:
The Michel-17 monoclonal antibody specifically reacts with mouse CD83, a 45kDA type I transmembrane glycoprotein.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Rat IgG1
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
Cd83
Additional Names:
Cd83, Cd83
Ncbi Gene Id Number:
12522
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The Michel-17 monoclonal antibody specifically reacts with mouse CD83, a 45kDA type I transmembrane glycoprotein. CD83 is expressed mainly on activated lymphocytes and mature dendritic cells and it plays a role in T cell development. The Michel-17 antibody does not induce an activation signal on dendritic or T cells.
Background Reference 1:
Cramer, S. O., Trumpfheller, C., Mehlhoop, U., Mor, S., Fleischer, B., von Bonin, A. (2000). Activation-induced expression of murine CD83 on T cells and identification of a specific CD83 ligand on murine B cells.International immunology,12(9), 1347-1351.
Background Reference 2:
Wolenski, M., Cramer, S. O., Ehrlich, S., Steeg, C., Fleischer, B., Von Bonin, A. (2003). Enhanced Activation of CD83Positive T Cells*.Scandinavian journal of immunology,58(3), 306-311.
Background Reference 3:
Breloer, M., Fleischer, B. (2008). CD83 regulates lymphocyte maturation, activation and homeostasis.Trends in immunology,29(4), 186-194.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-317

List Size:
0.1 mg

List Price:

$467.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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