CD38 Antibody [HIT2] (APC)

CATALOG NUMBER: 76-753

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
APC
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
APC
Tested Applications:
Flow
Specificity:
The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Mouse IgG1, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
CD38
Additional Names:
T10, ADPRC 1, CD38
Ncbi Gene Id Number:
952
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, macrophages, dendritic cells, and thymocytes. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.
Background Reference 1:
Oliver, A. M., Martin, F., Kearney, J. F. (1997). Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells.The Journal of Immunology,158(3), 1108-1115.
Background Reference 2:
Bean, A. G., Godfrey, D. I., Ferlin, W. G., Santos-Argumedo, L., Parkhouse, R. M. E., Howard, M. C., Zlotnik, A. (1995). CD38 expression on mouse T cells: CD38 defines functionally distinct subsets of alpha -beta TCR+ CD4 CD8 thymocytes.International immunology,7(2), 213-221.
Background Reference 3:
Lund, F., Solvason, N., Grimaldi, J. C., Michael, R., Parkhouse, E., Howard, M. (1995). Murine CD38: an immunoregulatory ectoenzyme.Immunology today,16(10), 469-473.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-753

List Size:
25 tests

List Price:

$249.00

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