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CD48 Antibody [156-4H9]

CATALOG NUMBER: 76-757

Clonality:
Monoclonal
Tested Applications:
Flow, Functional Assays
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Tested Applications:
Flow, Functional Assays
Specificity:
The 156-4H9 monoclonal antibody specifically reacts with human CD48, a GPI-linked glycoprotein in the Ig superfamily.
Purification:
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality:
Monoclonal
Isotype:
Mouse IgG1
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C . Do not freeze.
Ncbi Official Symbol:
CD48
Additional Names:
BCM1, BLAST, hCD48, mCD48, BLAST1, SLAMF2, MEM-102, CD48
Ncbi Gene Id Number:
962
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 156-4H9 monoclonal antibody specifically reacts with human CD48, a GPI-linked glycoprotein in the Ig superfamily. CD48 was previously known as BCM1 in mice, Blast-1 in humans, and OX-45 in rats. Its ligands are CD2 and CD244 and it is expressed on leukocytes to the exclusion of non-hematopoietic cells and its expression increases in B cells upon activation.
Background Reference 1:
Kato, K., Koyanagi, M., Okada, H., Takanashi, T., Wong, Y. W., Williams, A. F., ... Yagita, H. (1992). CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation.The Journal of experimental medicine,176(5), 1241-1249.
Background Reference 2:
Qin, L., Chavin, K. D., Lin, J., Yagita, H., Bromberg, J. S. (1994). Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival.The Journal of experimental medicine,179(1), 341-346.
Background Reference 3:
Chavin, K. D., Qin, L., Lin, J., Woodward, J., Baliga, P., Kato, K., ... Bromberg, J. S. (1994). Anti-CD48 (murine CD2 ligand) mAbs suppress cell mediated immunity in vivo.International immunology,6(5), 701-709.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-757

List Size:
0.5 mg

List Price:

$627.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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