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46-489 (0.3ug/ml) staining of Human Bone Marrow lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
46-489 (0.3ug/ml) staining of Human Bone Marrow lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

THRB Antibody

CATALOG NUMBER: 46-489

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Goat
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Goat
Species Reactivity:
Human
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog
Immunogen:
The immunogen for this antibody is: C-REELQKSIGHKP
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Approx 50+60kDa bands observed in Human Bone Marrow lysates (calculated MW of 52.8kDa according to NP_NP_000452.2 and of 54.5kDa according to EAW64350.1). Recommended concentration: 0.3-1ug/ml
Specificity:
This antibody is not expected to cross-react to THRA.
Positive Control 1:
Human Bone Marrow Lysate
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Storage Conditions:
Aliquot and store at -20°C. Minimize freezing and thawing.
Ncbi Official Symbol:
THRB
Additional Names:
THRB, thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian), ERBA-BETA, ERBA2, GRTH, MGC126109, MGC126110, NR1A2, THR1, THRB1, THRB2, avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, generalized resistance to thyroid hormone, oncogene ERBA2, thyroid hormone receptor beta 1, thyroid hormone receptor, beta
Protein Accession Number:
NP_000452.2
Protein Gi Number:
40806162
Ncbi Gene Id Number:
7068
Background Reference 1:
Kim JH, Park TS, Baek HS, Kim GH, Yoo HW, Park JH. A newly identified insertion mutation in the thyroid hormone receptor-beta genein a Korean family with generalized thyroid hormone resistance. J Korean Med Sci. 2007 Jun;22(3):560-3.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

46-489

List Size:
0.1 mg

List Price:

$469.00

Out of stock

Datasheet
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