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Dopamine Decarboxylase Antibody
Dopamine Decarboxylase Antibody

Dopamine Decarboxylase Antibody

CATALOG NUMBER: XPS-2000

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Bovine, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Bovine, Rat
Immunogen:
DOPA Decarboxylase polyclonal antibody was raised against a SDS denatured, recombinant bovine aromatic DDC expressed in E. coli and purified from inclusion bodies.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Applications include Dot Blots (DB) and Western Blots (WB). Recognizes DDC in rat adrenal medulla and caudate. When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB.
Specificity:
Dopamine Decarboxylase antibody is specific immunolabeling of the ~55k DDC protein in Western blots of rat adrenal medulla.
Predicted Molecular Weight:
55
Purification:
Affinity Purified
Clonality:
Polyclonal
physical-state:
Liquid
Concentration:
batch dependent
Storage Conditions:
For long term storage –80°C is recommended, but shorter term storage at –20°C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.
Ncbi Official Symbol:
DDC
Protein Accession Number:
P27718
Protein Gi Number:
125987819
Ncbi Gene Id Number:
280762
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Aromatic L-amino acid decarboxylase (AADC; DOPA decarboxylase; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin. It is also involved in the biosynthesis of trace amines.
Background Reference 1:
Haycock, J.W., Becker, L., Ang, L., Furukawa, Y., Hornykiewicz, O., and Kish, S.J., "Marked disparity between age-related changes in dopamine and other presynaptic dopaminergic markers in human striatum," J. Neurochem. 87 (2003) 574 - 585.
Background Reference 2:
Waymire, J.C. and Haycock, J.W. "Lack of regulation of aromatic L-amino acid decarboxylase in intact bovine chromaffin cells," J. Neurochem. 81 (2002) 589 - 593.
Background Reference 3:
Berry, M.D., Juorio, A.V., Li, X.M., and Boulton, A.A. "Aromatic L-amino acid decarboxylase: a neglected and misunderstood enzyme," Neurochem. Res. 21 (1996) 1075 -1087.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

XPS-2000

List Size:
0.1 mL

List Price:

$540.00

Datasheet
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