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STIM-1 Antibody

CATALOG NUMBER: 39-874

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Sheep
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Sheep
Species Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a region near the N-terminus.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
ELISA, Western (immuno) blotting, Immunostaining (in testing)
Purification:
Affinity Purified
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Concentration:
batch dependent
Ncbi Official Symbol:
STIM1
Additional Names:
Stromal Interaction Molecule 1, GOK, TAM, IMD10, D11S4896E
Protein Accession Number:
EAX02580
Protein Gi Number:
209572721
Ncbi Gene Id Number:
6786
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
STIM-1 is a component of the Ca sensor/channel. It associates with ORAI-1 and form a essential complex involved in store-operated channels. STIM1 activates Ca(2+) influx via Orai1 channels. Expression of STIM and Orai proteins are found in many cell types and knock-out mice lack viability.
Background Reference 1:
Williams RT, Senior PV, Van Stekelenburg L, Layton JE, Smith PJ, Dziadek MA., Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation., Biochim Biophys Acta. 2002 Apr 1;1596(1):131-137
Background Reference 2:
Dziadek MA, Johnstone LS., Biochemical properties and cellular localisation of STIM proteins., Cell Calcium. 2007 Aug;42(2):123-32.
Background Reference 3:
Frischauf I, Schindl R, Derler I, Bergsmann J, Fahrner M, Romanin C.,.The STIM/Orai coupling machinery., Channels (Austin). 2008 Jul-Aug;2(4):261-8

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

39-874

List Size:
0.1 mg

List Price:

$626.00

Datasheet
Shipping Info

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