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E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

RAC1 Antibody

CATALOG NUMBER: XW-7987

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Bovine, Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Bovine, Human, Mouse
Immunogen:
1-192
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
RAC1 antibody can be used for the detection of Ras-related C3 botulinum toxin substrate 1 by Western Blot.
Predicted Molecular Weight:
21.5 kDa (calculated)
Purification:
Immunoaffinity Purified
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
RAC1 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RAC1
Additional Names:
TC25, MIG5, Ras-related C3 botulinum toxin substrate 1, Cell migration-inducing gene 5 protein, Rasrelated C3 botulinum toxin substrate 1, p21-Rac1, Ras-like protein TC25
Protein Accession Number:
NP_008839.2
Protein Gi Number:
9845511
Ncbi Gene Id Number:
5879
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
FUNCTION: Isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins. It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish effector interaction.
SUBUNIT: Interacts with the GEF proteins PREX1, DOCK1 and DOCK2, which promote the exchange between GDP and GTP, and therefore activate it. Interacts with PARD6A, PARD6B and PARD6G in a GTP-dependent manner. Part of a quaternary complex containing PARD3, some PARD6 protein (PARD6A, PARD6B or PARD6G) and some atypical PKC protein (PRKCI or PRKCZ), which plays a central role in epithelial cell polarization. Found in a trimeric complex composed of DOCK1 and ELMO1, which plays a central role in phagocytosis of apoptotic cells. Interacts with RALBP1 via its effector domain. Interacts with PLXNB1. Part of a complex with MAP2K3, MAP3K3 and CCM2 (By similarity). Interacts with BAIAP2.
SUMMARY:

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7987

List Size:
0.05 mg

List Price:

$565.00

Datasheet
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