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Western blot analysis of lysed extracts from HeLa cells untreated or treated with starvation using α-catenin (Phospho-Ser641).
Western blot analysis of lysed extracts from HeLa cells untreated or treated with starvation using α-catenin (Phospho-Ser641).

a catenin (phospho Ser641) Antibody

CATALOG NUMBER: 79-503

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
a-catenin (Phospho-Ser641) antibody was raised against a peptide sequence around phosphorylation site of serine 641 (D-D-S (p) -D-F) derived from Human α-catenin.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of α-catenin only when phosphorylated at serine 641.
Predicted Molecular Weight:
100 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
CTNNA1
Additional Names:
CAP102, JNKK1, MEK4, MKK4, PRKMK4, SEK1, SERK1, SKK1, Cadherin-associated protein, Alpha E-catenin, NY-REN-13 antigen
Protein Accession Number:
NP_001894.2
Protein Gi Number:
55770844
Ncbi Gene Id Number:
1495
Background:
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. May play a crucial role in cell differentiation.
Background Reference 1:
Hwang, S. G. et al. (2005) J. Biol. Chem. 280, 12758-12765Drees, F. et al. (2005) Cell 123, 903-915. Yamada, S. et al. (2005) Cell 123, 889-901. Kobielak, A. and Fuchs, E. (2004) Nat. Rev. Mol. Cell Biol. 5, 614-625.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-503

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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