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Western blot analysis of lysed extracts from Rat and Mouse brain tissue using Adiponectin Antibody.
Western blot analysis of lysed extracts from Rat and Mouse brain tissue using Adiponectin Antibody.

Adiponectin Antibody

CATALOG NUMBER: 79-764

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Adiponectin antibody was raised against a peptide sequence around aa.235~239 (T-G-F-L-L) derived from Human Adiponectin.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of total Adiponectin protein.
Predicted Molecular Weight:
27 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
ADIPOQ
Additional Names:
ACDC, ADPN, APM1, APM-1, GBP28, ACRP30, ADIPQTL1, ACDC
Protein Accession Number:
NP_001171271.1
Protein Gi Number:
295317372
Ncbi Gene Id Number:
9370
Background:
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-κ-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Background Reference 1:
Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., Mori Y., Ide T., Murakami K., Yoda M. Kadowaki T. Nat. Med. 7:941-946 (2001) Richards A. A., Stephens T., Charlton H. K., Jones A., Macdonald G. A., Prins J. B., Whitehead J. P. Mol. Endocrinol. 20:1673-1687 (2006)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-764

List Size:
0.1 mg

List Price:

$370.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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