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EPHA3/4/5 (phospho Tyr779/833) Antibody

CATALOG NUMBER: 79-843

Clonality:
Polyclonal
Tested Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
EPHA3/4/5 (phospho Tyr779/833) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 779/833 (E-A-Y (p)-T-T)/ (Q-D-V (p)-I-K) derived from Human EPHA3/4/5.
Conjugate:
Unconjugated
Tested Applications:
IHC
Specificity:
The antibody detects endogenous levels of EPHA3/4/5 only when phosphorylated at tyrosine 779/833.
Predicted Molecular Weight:
110 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
EPHA3, EPHA4
Additional Names:
EPA3, ETK, HEK, MEK4, REK
Protein Accession Number:
NP_004429.1
Protein Gi Number:
21361241
Ncbi Gene Id Number:
2042;2043
Background:
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands.
Background Reference 1:
Wicks I.P., Proc. Natl. Acad. Sci. U.S.A. 89:1611-1615(1992).
Background Reference 2:
Chiari R., Cancer Res. 60:4855-4863(2000).
Background Reference 3:
Boyd A.W., J. Biol. Chem. 267:3262-3267(1992).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-843

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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