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Western blot analysis of extracts from HepG2 cells treated with Nocodazole using Phospho-Adrenergic Receptor beta2 (Ser346) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from HepG2 cells treated with Nocodazole using Phospho-Adrenergic Receptor beta2 (Ser346) Antibody. The lane on the right is treated with the antigen-specific peptide.

Adrenergic Receptor beta2 (phospho Ser346) Antibody

CATALOG NUMBER: 80-019

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Adrenergic Receptor beta2 (phospho Ser346) antibody was raised against a peptide sequence around phosphorylation site of serine 346 (R-S-S (p)-L-K) derived from Human Adrenergic Receptor beta2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous level of Adrenergic Receptor beta2 only when phosphorylated at serine 346.
Predicted Molecular Weight:
40 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
ADRB2
Additional Names:
ADRB2R, B2AR, adrenergic receptor, beta-2,
Protein Accession Number:
NP_000015.1
Protein Gi Number:
4501969
Ncbi Gene Id Number:
154
Background:
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Background Reference 1:
Gao S, Malbon C, Wang HY (2014) J Mol Signal 9, 3
Background Reference 2:
24690384 Curated Info
Background Reference 3:
Vistein R, Puthenveedu MA (2013) Proc Natl Acad Sci U S A 110, 15289-94
Background Reference 4:
Gimenez LE, et al. (2012) J Biol Chem 287, 9028-40

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

80-019

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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