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Bcl-xL Antibody [7B2.5] (Biotin)

CATALOG NUMBER: 99-618

Clonality:
Monoclonal
Tested Applications:
Flow, ICC, IHC-Fr, IHC-P, IP
Host Species:
Mouse
Species Reactivity:
Human, Mouse, Rat, Rhesus Monkey
Conjugate:
Biotin
Specifications
Host Species:
Mouse
Species Reactivity:
Human, Mouse, Rat, Rhesus Monkey
Immunogen:
Recombinant human Bcl-xS
Conjugate:
Biotin
Tested Applications:
Flow, ICC, IHC-Fr, IHC-P, IP
Application Note:
Bcl-xL Antibody [7B2.5] for use in flow cytometry, immunohistochemistry / immunocytochemistry, ELISA, western blotting, and immunoprecipitation assays.
Specificity:
Bcl-xL
Clonality:
Monoclonal
Isotype:
IgG3
physical-state:
Liquid
Buffer:
Supplied in PBS/NaN3
Concentration:
0.1 mg/mL
Storage Conditions:
Store vial at 2-8°C
Ncbi Official Symbol:
BCL2L1
Additional Names:
Apoptosis regulator Bcl-X, Bcl-2-like 1 protein, BCL2L1
Protein Accession Number:
Q07817
Ncbi Gene Id Number:
598
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein, Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

99-618

List Size:
0.1 mg

List Price:

$540.00

Datasheet
Shipping Info

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