Bcl-2 Antibody [10C4]

CATALOG NUMBER: 99-624

Clonality:
Monoclonal
Tested Applications:
Flow
Host Species:
Mouse
Species Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Mouse, Rat
Immunogen:
Murine Bcl-2 peptide (a.a. 61-76)
Conjugate:
Unconjugated
Tested Applications:
Flow
Application Note:
Bcl-2 Antibody [10C4] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and immunoprecipitation assays.
Specificity:
Bcl-2
Clonality:
Monoclonal
Isotype:
IgG1
physical-state:
Liquid
Buffer:
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration:
0.1 mg/mL
Storage Conditions:
Store vial at 2-8°C
Ncbi Official Symbol:
Bcl2
Additional Names:
B cell leukemia 2
Protein Accession Number:
P10417
Ncbi Gene Id Number:
12043;24224
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Bcl-2 is a 26 kDa member of the family of proteins involved in regulation of programmed cell death, or apoptosis. It is expressed in a variety of both normal and neoplastic tissues and appears to be membrane-bound since it is detectable in crude membrane and nuclear fractions, but not in the soluble fraction of cell lysates. Overexpression of Bcl-2 can prevent apoptosis, while formation of heterodimers with Bax, another Bcl-2-related protein, inhibits Bcl-2’s ability to promote cell survival.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

99-624

List Size:
0.1 mg

List Price:

$391.00

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