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ZC3H12A (CT) Peptide

CATALOG NUMBER: 9547P

Tested Applications:
Blocking
Specifications
Peptide Aa Location:
14 amino acids near the carboxyl terminus of human ZC3H12A.
Species:
Human
Tested Applications:
Blocking
Application Note:
ZC3H12A (CT) Peptide is used for blocking the activity of ZC3H12A (CT) Antibody.
physical-state:
Liquid
Buffer:
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Concentration:
200 ug/mL
Storage Conditions:
Store SARS-CoV-2 (COVID-19) Spike Q493R G496S Q498R N501Y Y505H Peptide (Omicron) at -20°C, stable for one year.
Ncbi Official Symbol:
ZC3H12A
Additional Names:
ZC3H12A Antibody: Endoribonuclease ZC3H12A, Monocyte chemotactic protein-induced protein 1, MCP-induced protein 1, MCPIP-1, Zinc finger CCCH domain-containing protein 12A
Protein Accession Number:
Q5D1E7.2
Protein Gi Number:
190485853
Ncbi Gene Id Number:
80149
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ZC3H12A Antibody: ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis. ZC3H12A inhibits the Wnt/beta-catenin signaling pathway activity and modulates epithelial-mesenchymal transition during clear cell renal cell carcinoma progression by targeting miRNAs. ZC3H12A ribonuclease can bind and cleave AURKA mRNA in MYCN-amplified neuroblastoma cells. ZC3H12A is a novel link between diabetogenic conditions and impaired insulin secretory capacity. ZC3H12A overexpression in human neuroblastoma cell lines causes cell-cycle arrest by G1/S checkpoint block.
Background Reference 1:
Gorka et al. Oncogene. 2021; 40(50):6720-6735
Background Reference 2:
Nowak et al. RNA Biol. 2021; 18(1):144-156
Background Reference 3:
Tyka et al. Biochim Biophys Acta Mol Basis Dis. 2021; 1867(10):166199
Background Reference 4:
Boratyn et al. J Cell Biochem. 2020; 121(5-6);3406-3425

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

9547P

List Size:
0.05 mg

List Price:

$119.00

Datasheet
Shipping Info

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