Start Your Project

🛍️Explore our Promotions page to discover current deals, limited-time offers, and more!🌟

Confocal imaging of Mouse primary hippocampal neuron cells(treated with Alpha-Synuclein Fibrils) and Mouse primary hippocampal neuron cells(treated with PBS) using Alpha-synuclein Truncation 1-119 mAb [MJFF-C-24D2] followed by a further incubation with Goat anti-Rabbit IgG (H+L), AlexaFluor 488 (Green). DAPI was used for nuclear staining (Blue). Objective: 60x.
Confocal imaging of Mouse primary hippocampal neuron cells(treated with Alpha-Synuclein Fibrils) and Mouse primary hippocampal neuron cells(treated with PBS) using Alpha-synuclein Truncation 1-119 mAb [MJFF-C-24D2] followed by a further incubation with Goat anti-Rabbit IgG (H+L), AlexaFluor 488 (Green). DAPI was used for nuclear staining (Blue). Objective: 60x.

Alpha-synuclein Truncation 1-119 Recombinant Antibody [MJFF-C-24D2] (83-521)

CATALOG NUMBER: 83-521

Clonality:
Monoclonal
Tested Applications:
ELISA, IF/ICC, Slot blot
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IF/ICC, Slot blot
Application Note:
IF/ICC,1:200 - 1:1000, Slot blot,1:500 - 1:1000, ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Predicted Molecular Weight:
14kDa
purification:
Affinity purification
Clonality:
Monoclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
Buffer: PBS with 0.09% Sodium azide,0.05% BSA,50% glycerol,pH7.3.
Concentration:
Batch dependent
Storage Conditions:
Store at -20℃. Avoid freeze / thaw cycles.
Ncbi Official Symbol:
SNCA
Additional Names:
PD1; NACP; PARK1; PARK4
Protein Accession Number:
P37840
Ncbi Gene Id Number:
6622
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Target background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Alpha-synuclein is a neuronal protein that plays many roles in synaptic activity such as membrane trafficking of synaptic vesicles and neurotransmitter release. Multiplications in SNCA have been implicated in genetic forms of Parkinson disease and pathological post-translational modifications of alpha-synuclein are a hallmark of Parkinson’s disease. These modifications include phosphorylation, nitration, acetylation, truncation, and aggregation. C-terminal truncations of alpha-synuclein lead to increased aggregation. Evidence for the 1-119 truncation in brains of patients with Parkinson’s disease, Lewy Body Dementia (LBD), Multiple Systems Atrophy (MSA), and Alzheimer’s disease.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

83-521

List Size:
100 uL

List Price:

$510.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products

HIV-1 p24 Antibody [9D2F6] (HRP)
HIV-1 p24 Antibody [9D2F6] (HRP)

CATALOG NUMBER: PM-7369-HRP

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [9D2F6]
HIV-1 p24 Antibody [9D2F6]

CATALOG NUMBER: PM-7369