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Anti-Snake Venom Antibody (C08)

CATALOG NUMBER: 31-608

Clonality:
Monoclonal
Tested Applications:
ELISA
Host Species:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Human
Conjugate:
Unconjugated
Tested Applications:
ELISA
Application Note:
ELISA: 1:2000-1:20000
Specificity:
Alpha-cobratoxin
purification:
Protein A/G purified from cell culture supernatant.
Clonality:
Monoclonal
Isotype:
IgG1
physical-state:
Liquid
Buffer:
0.01M PBS, pH 7.4.
Concentration:
Batch dependent
Storage Conditions:
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Additional Names:
Alpha-cobratoxin
Protein Accession Number:
P01391
Background:
Alpha-cobratoxin is a ~7 kDa protein. Monomer: binds with high affinity to muscular (alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND) nAChR (tested on Torpedo californica, Kd=0.2-4.5 nM) and neuronal alpha-7/CHRNA7 nicotinic acetylcholine receptors (Kd=13-105 nM). Also inhibits GABA(A) channels. Heteropentamer targets studied are composed of alpha-1-beta-3-gamma-2 (GABRA1-GABRB3-GABRG2) subunits (IC(50)=236 nM), alpha-1-beta-2-gamma-2 (GABRA1-GABRB2-GABRG2) subunits (IC(50)=469 nM), alpha-2-beta-2-gamma-2 (GABRA2-GABRB2-GABRG2) subunits (IC(50)=485 nM), alpha-5-beta-3-gamma-2 (GABRA5-GABRB3-GABRG2) subunits (IC(50)=635 nM), and alpha-2-beta-3-gamma-2 (GABRA2-GABRB3-GABRG2) subunits (IC(50)=1099 nM) (activated by 10 uM GABA).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

31-608

List Size:
0.1 mg

List Price:

$519.00

Datasheet
Shipping Info

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