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Recombinant Human RAMP3(M33L) Protein was determined by SDS-PAGE with Coomassie Blue.
Measured by its binding ability in a functional ELISA. Immobilized Human RAMP3(M33L) at 2 μg/mL (100 μL/well) can bind RAMP3 Rabbit pAb with a linear range of 0.10-8.48 ng/mL.
Recombinant Human RAMP3(M33L) Protein was determined by SDS-PAGE with Coomassie Blue.

Human RAMP3(M33L) Recombinant Protein (85-136)

CATALOG NUMBER: 85-136

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
CHO cells
Species:
Human
source-species:
CHO cells
Recombinant Protein Sequence:
Arg24-Val118
Fusion Tag:
C-8×His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
11.89 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human RAMP3(M33L) at 2 μg/mL (100 μL/well) can bind RAMP3 Rabbit pAb with a linear range of 0.10-8.48 ng/mL.
Purity:
≥ 95 % as determined by SDS-PAGE.
Endotoxin:
< 0.1 EU/μg of the protein by LAL method.
physical-state:
Lyophilized
Buffer:
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Storage Conditions:
Store at -70°C. This product is stable at ≤ -70°C for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.
Additional Names:
RAMP3,Receptor activity-modifying protein 3,RAMP3-H
Protein Accession Number:
NP_005847.1
Ncbi Gene Id Number:
10268
Background:
RAMP3 belongs to the RAMP family. Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL), calcitonin receptor (CALCR) and G-protein coupled estrogen receptor 1 (GPER1) .Required for the transport of CALCRL and GPER1 receptors to the plasma membrane .Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner.Together with CALCRL, form a receptor complex for adrenomedullin/ADM and intermedin/ADM2 .Together with CALCR, act as a receptor complex for amylin/IAPP.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

85-136

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $168.00 through $420.00

Datasheet
Shipping Info

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