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Recombinant Human BMPR-1B/ALK-6/CDw293 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
Immobilized Human BMP2 at 4 μg/mL (100 μL/well) can bind Human BMPRIB with a linear range of 20-338ng/mL.
Recombinant Human BMPR1B inhibits rhBMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells.The ED<sub>50</sub> for this effect is 0.6-2.3 μg/mL in the presence of 30 ng/mL of rhBMP-4.
Recombinant Human BMPR-1B/ALK-6/CDw293 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

Human BMPR-1B/ALK-6/CDw293 Recombinant Protein (85-317)

CATALOG NUMBER: 85-317

Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Lys14-Arg126
Fusion Tag:
C-hFc&His
Tested Applications:
Bioactivity Test, ELISA, Immunogen, SDS-PAGE, WB
Application Note:
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity Test
Predicted Molecular Weight:
39.50 kDa
Biological Activity:
1.Measured by its binding ability in a functional ELISA. Immobilized Human BMP2 at 4 μg/mL (100 μL/well) can bind Human BMPRIB with a linear range of 20-338 ng/mL.
2.Measured by its ability to inhibit rhBMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells.The ED50 for this effect is 0.6-2.3 μg/mL in the presence of 30 ng/mL of rhBMP-4.
Purity:
≥ 90 % as determined by SDS-PAGE.
Endotoxin:
< 0.1 EU/μg of the protein by LAL method.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Storage Conditions:
Store at -20°C.Store the lyophilized protein at -20°C to -80 °C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Additional Names:
ALK-6,ALK6,AMDD,BDA1D,BDA2,CDw293,BMPR1B, ALK-6, ALK6, AMDD, BDA1D, BDA2, CDw293, bone morphogenetic protein receptor type-1B
Protein Accession Number:
NP_001194.1
Ncbi Gene Id Number:
658

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

85-317

List Size:
0.01 mg, 0.05 mg

List Price:

Price range: $112.00 through $252.00

Datasheet
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