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Western blot analysis in mouse testis tissue lysates (15ug/lane).This demonstrates the detected BRWD2 protein (arrow).
Flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Western blot analysis in mouse testis tissue lysates (15ug/lane).This demonstrates the detected BRWD2 protein (arrow).

BRWD2 Antibody

CATALOG NUMBER: 62-018

Clonality:
Polyclonal
Tested Applications:
Flow, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This BRWD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 544-572 amino acids from the Central region of human BRWD2.
Conjugate:
Unconjugated
Tested Applications:
Flow, WB
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
Predicted Molecular Weight:
137 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
WDR11
Additional Names:
WD repeat-containing protein 11, Bromodomain and WD repeat-containing protein 2, WD repeat-containing protein 15, WDR11, BRWD2, KIAA1351, WDR15
Protein Accession Number:
Q9BZH6
Protein Gi Number:
17368715
Ncbi Gene Id Number:
55717
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
WDR11 is a member of the WD repeat proteinfamily. WD repeats are minimally conserved regions of approximately40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),which may facilitate formation of heterotrimeric or multiproteincomplexes. Members of this family are involved in a variety ofcellular processes, including cell cycle progression, signaltransduction, apoptosis, and gene regulation. This gene is locatedin the chromosome 10q25-26 region, which is frequently deleted ingliomas and tumors of other tissues, and is disrupted by thet(10;19) translocation rearrangement in glioblastoma cells. Thegene location suggests that it is a candidate gene for the tumorsuppressor locus.
Background Reference 1:
Katoh, M., et al. Int. J. Mol. Med. 11(5):579-583(2003)
Background Reference 2:
Katoh, M., et al. Int. J. Oncol. 22(5):1155-1159(2003)
Background Reference 3:
Chernova, O.B., et al. Oncogene 20(38):5378-5392(2001)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

62-018

List Size:
400 ul

List Price:

$469.00

Out of stock

Datasheet
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