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Western blot analysis in mouse heart tissue lysates (35ug/lane).
Western blot analysis in mouse heart tissue lysates (35ug/lane).

CLDN6 Antibody

CATALOG NUMBER: 55-362

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish
Immunogen:
This CLDN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human CLDN6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
23 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CLDN6
Additional Names:
Claudin-6, Skullin, CLDN6
Protein Accession Number:
P56747
Protein Gi Number:
90183180
Ncbi Gene Id Number:
9074
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Tight junctions represent one mode of cell-to-celladhesion in epithelial or endothelial cell sheets, formingcontinuous seals around cells and serving as a physical barrier toprevent solutes and water from passing freely through theparacellular space. These junctions are comprised of sets ofcontinuous networking strands in the outwardly facing cytoplasmicleaflet, with complementary grooves in the inwardly facingextracytoplasmic leaflet. This gene encodes a component of tightjunction strands, which is a member of the claudin family. Theprotein is an integral membrane protein and is one of the entrycofactors for hepatitis C virus. The gene methylation may beinvolved in esophageal tumorigenesis. This gene is adjacent toanother family member CLDN9 on chromosome 16.
Background Reference 1:
Wu, Q., et al. Eur. J. Cancer Prev. 19(3):186-194(2010)
Background Reference 2:
Kleinschmidt-DeMasters, B.K., et al. Am. J. Surg. Pathol. 34(3):341-354(2010)
Background Reference 3:
Rendon-Huerta, E., et al.Gastrointest Cancer 41(1):52-59(2010)
Background Reference 4:
Wu, Q., et al. Zhonghua Yi Xue Za Zhi 90(6):407-412(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-362

List Size:
200 ul

List Price:

$495.00

Datasheet
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