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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

FOLR3 Antibody

CATALOG NUMBER: 57-159

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This FOLR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human FOLR3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
28 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
FOLR3
Additional Names:
Folate receptor gamma, FR-gamma, Folate receptor 3, FOLR3
Protein Accession Number:
P41439
Protein Gi Number:
1169723
Ncbi Gene Id Number:
2352
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the folate receptor (FOLR)family, members of which have a high affinity for folic acid andfor several reduced folic acid derivatives, and mediate delivery of5-methyltetrahydrofolate to the interior of cells. This geneincludes two polymorphic variants; the shorter one has two basedeletion in the CDS, resulting in a truncated polypeptide, comparedto the longer one. Both protein products are constitutivelysecreted in hematopoietic tissues and are potential serum markerfor certain hematopoietic malignancies. The longer protein has a71% and 79% sequence homology with the FOLR1 and FOLR2 proteins,respectively.
Background Reference 1:
O'Byrne, M.R., et al. Birth Defects Res. PartClin. Mol. Teratol. 88(8):689-694(2010)
Background Reference 2:
Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Background Reference 3:
Boyles, A.L., et al. Genet. Epidemiol. 33(3):247-255(2009)
Background Reference 4:
Franke, B., et al. Birth Defects Res. PartClin. Mol. Teratol. 85(3):216-226(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-159

List Size:
400 ul

List Price:

$495.00

Datasheet
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