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Western blot analysis of lysate from Jurkat cell line, using GLRB Antibody at 1:1000 at each lane.
Western blot analysis of lysate from Jurkat cell line, using GLRB Antibody at 1:1000 at each lane.

GLRB Antibody

CATALOG NUMBER: 58-104

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This GLRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human GLRB.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
56 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GLRB
Additional Names:
Glycine receptor subunit beta, Glycine receptor 58 kDa subunit, GLRB
Protein Accession Number:
P48167
Protein Gi Number:
1346173
Ncbi Gene Id Number:
2743
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes the beta subunit of the glycinereceptor, which is a pentamer composed of alpha and beta subunits.The receptor functions as a neurotransmitter-gated ion channel,which produces hyperpolarization via increased chloride conductancedue to the binding of glycine to the receptor. Mutations in thisgene cause startle disease, also known as hereditary hyperekplexiaor congenital stiff-person syndrome, a disease characterized bymuscular rigidity. Alternative splicing results in multipletranscript variants.
Background Reference 1:
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Background Reference 2:
Wheeler, H.E., et al. PLoS Genet.(10), E1000685 (2009) :
Background Reference 3:
Ziegler, E., et al. Naunyn Schmiedebergs Arch. Pharmacol. 380(4):277-291(2009)
Background Reference 4:
Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-104

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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