ICAM3 Antibody

CATALOG NUMBER: 57-213

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ICAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 amino acids from the Central region of human ICAM3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ICAM3
Additional Names:
Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, CD50, ICAM3
Protein Accession Number:
P32942
Protein Gi Number:
206729872
Ncbi Gene Id Number:
3385
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of theintercellular adhesion molecule (ICAM) family. All ICAM proteinsare type I transmembrane glycoproteins, contain 2-9immunoglobulin-like C2-type domains, and bind to the leukocyteadhesion LFA-1 protein. This protein is constitutively andabundantly expressed by all leucocytes and may be the mostimportant ligand for LFA-1 in the initiation of the immuneresponse. It functions not only as an adhesion molecule, but alsoas a potent signalling molecule.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Background Reference 3:
Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)
Background Reference 4:
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-213

List Size:
400 ul

List Price:

$495.00

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