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IL-20 Receptor 2 Antibody [20RNTC]

CATALOG NUMBER: 76-001

Clonality:
Monoclonal
Tested Applications:
Flow, ICC, WB
Host Species:
Rat
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rat
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Tested Applications:
Flow, ICC, WB
Specificity:
The 20RNTC monoclonal antibody specifically reacts with human and mouse interleukin-20 receptor 2 (IL-20R2 or IL-20Rb).
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality:
Monoclonal
Isotype:
Rat IgG2a, kappa
Physical State:
Liquid
Buffer:
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Storage Conditions:
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Ncbi Official Symbol:
IL20RB
Additional Names:
DIRS1, FNDC6, IL-20R2, Fndc6, Gm186, Il20R2, AV228068, IL20RB
Ncbi Gene Id Number:
53833;213208
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 20RNTC monoclonal antibody specifically reacts with human and mouse interleukin-20 receptor 2 (IL-20R2 or IL-20Rb). IL-20R2 is a class II cytokine receptor that pairs with IL-20R to form a receptor capable of binding IL-19, IL-20, or IL-24 and binds IL-20, or IL-24 when paired with IL-22R1. It is primarily found on epithelial originated cells such as those found in the skin or intestines.
Background Reference 1:
Blumberg, H., Conklin, D., Xu, W., Grossmann, A., Brender, T., Carollo, S., ... Chandrasekher, Y. A. (2001). Interleukin 20: discovery, receptor identification, and role in epidermal function.Cell,104(1), 9-19.
Background Reference 2:
Wahl, C., M, W., Leith, F., Adler, G., Oswald, F., Reimann, J., ... Wegenka, U. M. (2009). IL-20 receptor 2 signaling down-regulates antigen-specific T cell responses.The Journal of Immunology,182(2), 802-810.
Background Reference 3:
Dumoutier, L., Leemans, C., Lejeune, D., Kotenko, S. V., Renauld, J. C. (2001). Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types.The Journal of Immunology,167(7), 3545-3549.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

76-001

List Size:
0.1 mg

List Price:

$432.00

Datasheet
Shipping Info

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