iNOS (phospho Tyr151) Antibody

CATALOG NUMBER: 79-877

Clonality:
Polyclonal
Tested Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
iNOS (phospho Tyr151) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 151 (Q-Y-Y (p)-G-S) derived from Human iNOS .
Conjugate:
Unconjugated
Tested Applications:
IHC
Specificity:
The antibody detects endogenous levels of Inos only when phosphorylated at tyrosine 151.
Predicted Molecular Weight:
131 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
NOS2
Additional Names:
HEP-NOS, NOS2, inducible
Protein Accession Number:
NP_000616.3
Protein Gi Number:
1352513
Ncbi Gene Id Number:
4843
Background:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
Background Reference 1:
Geller D.A., Proc. Natl. Acad. Sci. U.S.A. 90:3491-3495(1993).
Background Reference 2:
Sherman P.A., Biochemistry 32:11600-11605(1993).
Background Reference 3:
Charles I.G., Proc. Natl. Acad. Sci. U.S.A. 90:11419-11423(1993).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-877

List Size:
0.1 mg

List Price:

$376.00

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