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Antibody used in WB on human LCL and mouse brains at 1:1000.
Antibody used in WB on Human 293T at 0.2-1 ug/ml.
Antibody used in IHC on human LCL and mouse brains at 1:500.
Antibody used in WB on human LCL and mouse brains at 1:1000.

OLIG2 Antibody

CATALOG NUMBER: 27-353

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human OLIG2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
OLIG2 antibody can be used for detection of OLIG2 by ELISA at 1:62500. OLIG2 antibody can be used for detection of OLIG2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Tranfected 293T Cell Lysate
Predicted Molecular Weight:
32 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store OLIG2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
OLIG2
Additional Names:
OLIG2, BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19
Protein Accession Number:
NP_005797
Protein Gi Number:
17978475
Ncbi Gene Id Number:
10215
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
OLIG2 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. OLIG2 is an essential regulator of ventral neuroectodermal progenitor cell fate. It is associated with T-cell acute lymphoblastic leukemia due to a chromosomal translocation t (14;21) (q11.2;q22). OLIG2 might play a role in learning deficits associated with Down syndrome.This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t (14;21) (q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background Reference 1:
Mitkus, S.N., Schizophr. Res. 98 (1-3), 129-138 (2008).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-353

List Size:
100 ul

List Price:

$519.00

Datasheet
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