PAFAH2 Antibody

CATALOG NUMBER: 59-174

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PAFAH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-276 amino acids from the Central region of human PAFAH2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
44 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PAFAH2
Additional Names:
Platelet-activating factor acetylhydrolase 2, cytoplasmic, Serine-dependent phospholipase A2, SD-PLA2, hSD-PLA2, PAFAH2
Protein Accession Number:
Q99487
Protein Gi Number:
6647691
Ncbi Gene Id Number:
5051
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes platelet-activating factoracetylhydrolase isoform 2, a single-subunit intracellular enzymethat catalyzes the removal of the acetyl group at the SN-2 positionof platelet-activating factor (identified as1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, thislipase exhibits a broader substrate specificity than simplyplatelet activating factor. Two other isoforms of intracellularplatelet-activating factor acetylhydrolase exist, and both aremulti-subunit enzymes. Additionally, there is a single-subunitserum isoform of this enzyme.
Background Reference 1:
Schmidt, E.B., et al. Atherosclerosis 196(1):420-424(2008)
Background Reference 2:
Umemura, K., et al. Stroke 38(3):1063-1068(2007)
Background Reference 3:
Unno, N., et al. J. Surg. Res. 134(1):36-43(2006)
Background Reference 4:
Marques, M., et al. J. Invest. Dermatol. 119(4):913-919(2002)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-174

List Size:
400 ul

List Price:

$495.00

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