PPP1R3B Antibody

CATALOG NUMBER: 59-734

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PPP1R3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human PPP1R3B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
33 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PPP1R3B
Additional Names:
Protein phosphatase 1 regulatory subunit 3B, Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL, Protein phosphatase 1 regulatory subunit 4, PP1 subunit R4, Protein phosphatase 1 subunit GL, PTG, PPP1R3B, PPP1R4
Protein Accession Number:
Q86XI6
Protein Gi Number:
74727837
Ncbi Gene Id Number:
79660
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein phosphatase-1 (PP1) catalytic subunit (PPP1CA;MIM 176875) is regulated by targeting subunits, such as PP1R3B.PP1R3B suppresses the rate at which PP1 dephosphorylates (i.e.,inactivates) glycogen phosphorylase (see PYGL; MIM 232700) andenhances the rate at which it activates glycogen synthase (seeGYS2; MIM 138571) (Doherty et al., 1995 [PubMed 7498521]).[suppliedby OMIM].
Background Reference 1:
Montori-Grau, M., et al. Biochem. J. 405(1):107-113(2007)
Background Reference 2:
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Background Reference 3:
Ceulemans, H., et al. Bioessays 24(4):371-381(2002)
Background Reference 4:
Doherty, M.J., et al. FEBS Lett. 375(3):294-298(1995)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-734

List Size:
400 ul

List Price:

$495.00

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