5HT3E Antibody

CATALOG NUMBER: 55-244

Clonality:
Polyclonal
Tested Applications:
Flow, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This 5HT3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the Central region of human 5HT3E.
Conjugate:
Unconjugated
Tested Applications:
Flow, WB
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
Predicted Molecular Weight:
51 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
HTR3E
Additional Names:
5-hydroxytryptamine receptor 3E, 5-HT3-E, 5-HT3E, Serotonin receptor 3E, HTR3E
Protein Accession Number:
A5X5Y0
Ncbi Gene Id Number:
285242
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The product of this gene belongs to the ligand-gated ionchannel receptor superfamily. HTR3E encodes a subunit E of thetype 3 receptor for 5-hydroxytryptamine (serotonin), a biogenichormone that functions as a neurotransmitter, a hormone, and amitogen. This receptor causes fast, depolarizing responses inneurons after activation. Genes encoding subunits C, D and E form acluster on chromosome 3. An alternative splice variant has beendescribed but its full length sequence has not been determined.
Background Reference 1:
Walstab, J., et al. J. Biol. Chem. 285(35):26956-26965(2010)
Background Reference 2:
Hammer, C., et al. Pharmacogenomics 11(7):943-950(2010)
Background Reference 3:
Lennertz, L., et al. Eur Neuropsychopharmacol 20(6):414-420(2010)
Background Reference 4:
Goecke, T.W., et al. Acta Obstet Gynecol Scand 89(1):7-14(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-244

List Size:
400 ul

List Price:

$495.00

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