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Western blot analysis in HepG2,Y79 cell line lysates (35ug/lane).
Western blot analysis in HepG2,Y79 cell line lysates (35ug/lane).

AADAT Antibody

CATALOG NUMBER: 55-064

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This AADAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human AADAT.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
47 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
AADAT
Additional Names:
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial, KAT/AadAT, 2-aminoadipate aminotransferase, 2-aminoadipate transaminase, Alpha-aminoadipate aminotransferase, AadAT, Kynurenine aminotransferase II, Kynurenine--oxoglutarate aminotransferase II, Kynurenine--oxoglutarate transaminase 2, Kynurenine--oxoglutarate transaminase II, AADAT, KAT2
Protein Accession Number:
Q8N5Z0
Protein Gi Number:
46395904
Ncbi Gene Id Number:
51166
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein that is highly similar tomouse and rat kynurenine aminotransferase II. The rat protein is ahomodimer with two transaminase activities. One activity is thetransamination of alpha-aminoadipic acid, a final step in thesaccaropine pathway which is the major pathway for L-lysinecatabolism. The other activity involves the transamination ofkynurenine to produce kynurenine acid, the precursor of kynurenicacid which has neuroprotective properties. Two alternativetranscripts encoding the same isoform have been identified,however, additional alternative transcripts and isoforms may exist.
Background Reference 1:
Han, Q., et al. Biosci. Rep. 28(4):205-215(2008)
Background Reference 2:
Rossi, F., et al. J. Biol. Chem. 283(6):3559-3566(2008)
Background Reference 3:
Han, Q., et al. J. Biol. Chem. 283(6):3567-3573(2008)
Background Reference 4:
Lamesch, P., et al. Genomics 89(3):307-315(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-064

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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