ABCC12 Antibody

CATALOG NUMBER: 56-913

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-752 amino acids from the Central region of human ABCC12.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
152 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ABCC12
Additional Names:
Multidrug resistance-associated protein 9, ATP-binding cassette sub-family C member 12, ABCC12, MRP9
Protein Accession Number:
Q96J65
Protein Gi Number:
161788999
Ncbi Gene Id Number:
94160
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the superfamily of ATP-bindingcassette (ABC) transporters and the encoded protein contains twoATP-binding domains and 12 transmembrane regions. ABC proteinstransport various molecules across extra- and intracellularmembranes. ABC genes are divided into seven distinct subfamilies:ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is amember of the MRP subfamily which is involved in multi-drugresistance. This gene and another subfamily member are arrangedhead-to-tail on chromosome 16q12.1. Increased expression of thisgene is associated with breast cancer.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Haimeur, A., et al. Curr. Drug Metab. 5(1):21-53(2004)
Background Reference 3:
Bera, T.K., et al. Proc. Natl. Acad. Sci. U.S.A. 99(10):6997-7002(2002)
Background Reference 4:
Yabuuchi, H., et al. Biochem. Biophys. Res. Commun. 288(4):933-939(2001)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-913

List Size:
400 ul

List Price:

$495.00

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