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Western blot analysis of extract from HL-60 cells using ABCG2 (CD338) Antibody.
Western blot analysis of extract from HL-60 cells using ABCG2 (CD338) Antibody.

ABCG2 (CD338) Antibody

CATALOG NUMBER: 79-673

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
ABCG2 (CD338) antibody was raised against a peptide sequence around aa.160~164 ( R-I-N-R-V) derived from Human ABCG2 (CD338).
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500
Specificity:
This antibody detects endogenous level of total ABCG2(CD338) protein.
Predicted Molecular Weight:
65 - 80 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
ABCG2
Additional Names:
MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, CD338, GOUT1, CDw338, UAQTL1, EST157481, MRX
Protein Accession Number:
NP_004818.2
Protein Gi Number:
62526033
Ncbi Gene Id Number:
9429
Background:
Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Background Reference 1:
Henriksen U., Gether U., Litman T. J. Cell Sci. 118:1417-1426 (2005) Wakabayashi K., Nakagawa H., Tamura A., Koshiba S., Hoshijima K., Komada M., Ishikawa T. J. Biol. Chem. 282:27841-27846 (2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-673

List Size:
0.1 mg

List Price:

$370.00

Datasheet
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