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Western blot analysis of extracts from COS7 cells treated with Adriamycin using Abl (Phospho-Tyr204) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from COS7 cells treated with Adriamycin using Abl (Phospho-Tyr204) Antibody. The lane on the right is treated with the antigen-specific peptide.

Abl (phospho Tyr204) Antibody

CATALOG NUMBER: 79-953

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Abl (phospho Tyr204) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 204 (K-L-Y (p)-V-S) derived from Human c-Abl.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous level of Abl only when phosphorylated at tyrosine 204.
Predicted Molecular Weight:
135 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
ABL1
Additional Names:
p150, c-ABL, EC 2.7.10.2
Protein Accession Number:
NP_005148.2
Protein Gi Number:
62362414
Ncbi Gene Id Number:
25
Background:
Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like WASF3 (involved in branch formation); ANXA1 (involved in membrane anchoring); DBN1, DBNL, CTTN, RAPH1 and ENAH (involved in signaling); or MAPT and PXN (microtubule-binding proteins).
Background Reference 1:
Meyn MA, et al. (2006) J Biol Chem 281, 30907-16
Background Reference 2:
Steen H, et al. (2003) Mol Cell Proteomics 2, 138-45
Background Reference 3:
Salomon AR, et al. (2003) Proc Natl Acad Sci U S A 100, 443-8

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-953

List Size:
0.1 mg

List Price:

$355.00

Out of stock

Datasheet
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