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Antibody used in IHC on Human kidney.
Antibody used in WB on Human Kidney at 2.5 ug/ml.
Antibody used in IHC on Human kidney.

ACCN3 Antibody

CATALOG NUMBER: 28-249

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ACCN3.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
ACCN3 antibody can be used for detection of ACCN3 by ELISA at 1:62500. ACCN3 antibody can be used for detection of ACCN3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10408 - Fetal Kidney Tissue Lysate
Predicted Molecular Weight:
58 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store ACCN3 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
ASIC3
Additional Names:
ACCN3, ACCN3, TNaC1, DRASIC, SLNAC1
Protein Accession Number:
NP_004760
Protein Gi Number:
4757710
Ncbi Gene Id Number:
9311
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
Background Reference 1:
Jones, N.G., et al., (2004) J. Neurosci. 24(48), 10974-9.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-249

List Size:
100 ul

List Price:

$473.00

Datasheet
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